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Response of I(Kr) and hERG Currents to the Antipsychotics Tiapride and Sulpiride
The human ether-a-go-go-related gene (hERG) channel is important for repolarization in human myocardium and is a common target for drugs that prolong the QT interval. We studied the effects of two antipsychotics, tiapride and sulpiride, on hERG channels expressed in Xenopus oocytes and also on delay...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Physiological Society and The Korean Society of Pharmacology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997416/ https://ncbi.nlm.nih.gov/pubmed/21165329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.5.305 |
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