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Response of I(Kr) and hERG Currents to the Antipsychotics Tiapride and Sulpiride

The human ether-a-go-go-related gene (hERG) channel is important for repolarization in human myocardium and is a common target for drugs that prolong the QT interval. We studied the effects of two antipsychotics, tiapride and sulpiride, on hERG channels expressed in Xenopus oocytes and also on delay...

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Hlavní autoři: Jo, Su-Hyun, Lee, So-Young
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997416/
https://ncbi.nlm.nih.gov/pubmed/21165329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.5.305
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