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Expression and Knockdown of Cellular Prion Protein (PrP(C)) in Differentiating Mouse Embryonic Stem Cells
The mammalian cellular prion protein (PrP(C)) is a highly conserved glycoprotein that may undergo conversion into a conformationally altered isoform (scrapie prion protein or PrP(Sc)), widely believed to be the pathogenic agent of transmissible spongiform encephalopathies (TSEs). Although much is kn...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997124/ https://ncbi.nlm.nih.gov/pubmed/20926176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2010.09.181 |
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