The specificity of UV-induced mutations at an endogenous locus in mammalian cells.
We have used a rapid in vivo recombinational method to clone and completely sequence 34 UV-induced mutants at the adenine phosphoribosyltransferase (APRT) locus of Chinese hamster ovary cells. Among the mutants recovered, 26 were single base substitutions including 17 G.C----A.T transitions and a si...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1987
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3480533/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9103 |
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