Roles for mycobacterial DinB2 in frameshift and substitution mutagenesis

Translesion synthesis by translesion polymerases is a conserved mechanism of DNA damage tolerance. In bacteria, DinB enzymes are the widely distributed promutagenic translesion polymerases. The role of DinBs in mycobacterial mutagenesis was unclear until recent studies revealed a role for mycobacter...

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Autors principals:	Pierre Dupuy, Shreya Ghosh, Allison Fay, Oyindamola Adefisayo, Richa Gupta, Stewart Shuman, Michael S Glickman
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2023-05-01
Col·lecció:	eLife
Matèries:	Mycobacterium smegmatis Mycobacterium tuberculoiss mutagenesis DNA damage response antimicrobial resistance
Accés en línia:	https://elifesciences.org/articles/83094
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