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Roles for mycobacterial DinB2 in frameshift and substitution mutagenesis

Translesion synthesis by translesion polymerases is a conserved mechanism of DNA damage tolerance. In bacteria, DinB enzymes are the widely distributed promutagenic translesion polymerases. The role of DinBs in mycobacterial mutagenesis was unclear until recent studies revealed a role for mycobacter...

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Príomhchruthaitheoirí: Pierre Dupuy, Shreya Ghosh, Allison Fay, Oyindamola Adefisayo, Richa Gupta, Stewart Shuman, Michael S Glickman
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: eLife Sciences Publications Ltd 2023-05-01
Sraith:eLife
Ábhair:
Rochtain ar líne:https://elifesciences.org/articles/83094
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