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ChIP on Chip: surprising results are often artifacts

BACKGROUND: The method of chromatin immunoprecipitation combined with microarrays (ChIP-Chip) is a powerful tool for genome-wide analysis of protein binding. However, a high background signal is a common phenomenon. RESULTS: Reinvestigation of the chromatin immunoprecipitation procedure led us to di...

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Detalhes bibliográficos
Main Authors: Waldminghaus, Torsten, Skarstad, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996942/
https://ncbi.nlm.nih.gov/pubmed/20602746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-414
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