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“Non-canonical protein-DNA interactions identified by ChIP are not artifacts”: response

BACKGROUND: Studies of protein association with DNA on a genome wide scale are possible through methods like ChIP-Chip or ChIP-Seq. Massive problems with false positive signals in our own experiments motivated us to revise the standard ChIP-Chip protocol. Analysis of chromosome wide binding of the a...

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Autors principals: Schindler, Daniel, Waldminghaus, Torsten
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870955/
https://ncbi.nlm.nih.gov/pubmed/24053571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-638
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