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ChIP on Chip: surprising results are often artifacts
BACKGROUND: The method of chromatin immunoprecipitation combined with microarrays (ChIP-Chip) is a powerful tool for genome-wide analysis of protein binding. However, a high background signal is a common phenomenon. RESULTS: Reinvestigation of the chromatin immunoprecipitation procedure led us to di...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996942/ https://ncbi.nlm.nih.gov/pubmed/20602746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-414 |
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