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A conserved domain regulates interactions of the v-fps protein-tyrosine kinase with the host cell.
All cytoplasmic protein-tyrosine kinases (PTKs) share a noncatalytic domain, termed SH2, which comprises approximately 100 residues located immediately N-terminal to the kinase domain. A linker in the AX9m mutant of Fujinami avian sarcoma virus (FSV) introduces a dipeptide insertion into the SH2 dom...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3480531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9064 |
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