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A conserved domain regulates interactions of the v-fps protein-tyrosine kinase with the host cell.

All cytoplasmic protein-tyrosine kinases (PTKs) share a noncatalytic domain, termed SH2, which comprises approximately 100 residues located immediately N-terminal to the kinase domain. A linker in the AX9m mutant of Fujinami avian sarcoma virus (FSV) introduces a dipeptide insertion into the SH2 dom...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: DeClue, J E, Sadowski, I, Martin, G S, Pawson, T
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299692/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3480531/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.9064
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