Microsomal glutathione transferase 1 exhibits one-third-of-the-sites-reactivity towards glutathione

The trimeric membrane protein microsomal glutathione transferase 1 (MGST1) possesses glutathione transferase and peroxidase activity. Previous data indicated one active site/trimer whereas structural data suggests three GSH-binding sites. Here we have determined ligand interactions of MGST1 by sever...

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Main Authors: Ålander, Johan, Lengqvist, Johan, Holm, Peter J., Svensson, Richard, Gerbaux, Pascal, van den Heuvel, Robert H.H., Hebert, Hans, Griffiths, William J., Armstrong, Richard N., Morgenstern, Ralf
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996728/
https://ncbi.nlm.nih.gov/pubmed/19416719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.04.009
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