Deficits in axonal transport precede ALS symptoms in vivo

ALS is a fatal neurodegenerative disease characterized by selective motor neuron death resulting in muscle paralysis. Mutations in superoxide dismutase 1 (SOD1) are responsible for a subset of familial cases of ALS. Although evidence from transgenic mice expressing human mutant SOD1(G93A) suggests t...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Bilsland, Lynsey G., Sahai, Erik, Kelly, Gavin, Golding, Matthew, Greensmith, Linda, Schiavo, Giampietro
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996651/
https://ncbi.nlm.nih.gov/pubmed/21059924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006869107
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares