Enthalpy-entropy compensations in drug-DNA binding studies.

We present a comparative study of calorimetrically derived thermodynamic profiles for the binding of a series of drugs with selected DNA host duplexes. We use these data to demonstrate that comparisons between complete thermodynamic profiles (delta G zero, delta H zero, delta S zero, delta Cp) are r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Breslauer, K J, Remeta, D P, Chou, W Y, Ferrante, R, Curry, J, Zaunczkowski, D, Snyder, J G, Marky, L A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2827160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.8922
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