Enthalpy-entropy compensations in drug-DNA binding studies.
We present a comparative study of calorimetrically derived thermodynamic profiles for the binding of a series of drugs with selected DNA host duplexes. We use these data to demonstrate that comparisons between complete thermodynamic profiles (delta G zero, delta H zero, delta S zero, delta Cp) are r...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1987
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2827160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.24.8922 |
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