Enthalpy-entropy compensations in drug-DNA binding studies.

We present a comparative study of calorimetrically derived thermodynamic profiles for the binding of a series of drugs with selected DNA host duplexes. We use these data to demonstrate that comparisons between complete thermodynamic profiles (delta G zero, delta H zero, delta S zero, delta Cp) are r...

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Main Authors: Breslauer, K J, Remeta, D P, Chou, W Y, Ferrante, R, Curry, J, Zaunczkowski, D, Snyder, J G, Marky, L A
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC299663/
https://ncbi.nlm.nih.gov/pubmed/2827160
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