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NITROPHORIN 2, A FIX(a)-DIRECTED ANTICOAGULANT, INHIBITS ARTERIAL THROMBOSIS WITHOUT IMPAIRING HEMOSTASIS
Nitrophorin 2 (NP2) is a 20 kDa lipocalin identified in the salivary gland of the blood sucking insect, Rhodnius prolixus. It functions as a potent inhibitor of the intrinsic pathway of coagulation upon binding to factor IX (FIX) or FIXa. Herein we have investigated the in vivo antithrombotic proper...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996477/ https://ncbi.nlm.nih.gov/pubmed/20838739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH10.1160/TH10-03-0186 |
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