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NITROPHORIN 2, A FIX(a)-DIRECTED ANTICOAGULANT, INHIBITS ARTERIAL THROMBOSIS WITHOUT IMPAIRING HEMOSTASIS

Nitrophorin 2 (NP2) is a 20 kDa lipocalin identified in the salivary gland of the blood sucking insect, Rhodnius prolixus. It functions as a potent inhibitor of the intrinsic pathway of coagulation upon binding to factor IX (FIX) or FIXa. Herein we have investigated the in vivo antithrombotic proper...

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Bibliografiska uppgifter
Huvudupphovsmän: Mizurini, Daniella M., Francischetti, Ivo M.B., Andersen, John F., Monteiro, Robson Q.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996477/
https://ncbi.nlm.nih.gov/pubmed/20838739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH10.1160/TH10-03-0186
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