Suppression of cFLIP by Lupeol, a Dietary Triterpene, Is Sufficient to Overcome Resistance to TRAIL-Mediated Apoptosis in Chemoresistant Human Pancreatic Cancer Cells

Overexpression of cellular FLICE-like inhibitory protein (cFLIP) is reported to confer chemoresistance in pancreatic cancer (PaC) cells. This study was designed to investigate the effect of lupeol, a dietary triterpene, on (a) apoptosis of tumor necrosis factor–related apoptosis-inducing ligand (TRA...

Full description

Saved in:
Bibliographic Details
Main Authors: Murtaza, Imtiyaz, Saleem, Mohammad, Adhami, Vaqar Mustafa, Hafeez, Bilal Bin, Mukhtar, Hasan
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996261/
https://ncbi.nlm.nih.gov/pubmed/19176377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2917
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items