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Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3 mediated inhibition of NF-κB

Death receptors of the tumor necrosis factor (TNF) receptor super family have been implicated in constitutive activation of Nuclear Factor kappa B (NF-κB) in pancreatic cancer (PaC) cells. In this study we demonstrate that fisetin, a natural flavonoid, induces apoptosis and inhibits invasion of chem...

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Bibliografski detalji
Glavni autori: Murtaza, Imtiyaz, Adhami, Vaqar Mustafa, Hafeez, Bilal Bin, Saleem, Mohammad, Mukhtar, Hasan
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944651/
https://ncbi.nlm.nih.gov/pubmed/19670328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24628
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