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Kinetic Isotope Effects in Asymmetric Reactions

Kinetic isotope effects are exquisitely sensitive probes of transition structure. As such, kinetic isotope effects offer a uniquely useful probe for the symmetry-breaking process that is inherent to stereoselective reactions. In this Concept article, we explore the role of steric and electronic effe...

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Detalhes bibliográficos
Main Authors: Giagou, Thomas, Meyer, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996239/
https://ncbi.nlm.nih.gov/pubmed/20669194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201001018
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