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Comparison of Deterministic and Stochastic Models of the lac Operon Genetic Network

The lac operon has been a paradigm for genetic regulation with positive feedback, and several modeling studies have described its dynamics at various levels of detail. However, it has not yet been analyzed how stochasticity can enrich the system's behavior, creating effects that are not observe...

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Detalhes bibliográficos
Main Authors: Stamatakis, Michail, Mantzaris, Nikos V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996131/
https://ncbi.nlm.nih.gov/pubmed/19186128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.028
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