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Deterministic and stochastic population-level simulations of an artificial lac operon genetic network

BACKGROUND: The lac operon genetic switch is considered as a paradigm of genetic regulation. This system has a positive feedback loop due to the LacY permease boosting its own production by the facilitated transport of inducer into the cell and the subsequent de-repression of the lac operon genes. P...

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Detalhes bibliográficos
Main Authors: Stamatakis, Michail, Zygourakis, Kyriacos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181209/
https://ncbi.nlm.nih.gov/pubmed/21791088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-301
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