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From Single-Cell Genetic Architecture to Cell Population Dynamics: Quantitatively Decomposing the Effects of Different Population Heterogeneity Sources for a Genetic Network with Positive Feedback Architecture
Phenotypic cell-to-cell variability or cell population heterogeneity originates from two fundamentally different sources: unequal partitioning of cellular material at cell division and stochastic fluctuations associated with intracellular reactions. We developed a mathematical and computational fram...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1877777/ https://ncbi.nlm.nih.gov/pubmed/17384073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.100271 |
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