Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

Within the healthy population, there is substantial, heritable, and interindividual variability in the platelet response. We explored whether a proportion of this variability could be accounted for by interindividual variation in gene expression. Through a correlative analysis of genome-wide platele...

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Autores principales: Goodall, Alison H., Burns, Philippa, Salles, Isabelle, Macaulay, Iain C., Jones, Chris I., Ardissino, Diego, de Bono, Bernard, Bray, Sarah L., Deckmyn, Hans, Dudbridge, Frank, Fitzgerald, Desmond J., Garner, Stephen F., Gusnanto, Arief, Koch, Kerstin, Langford, Cordelia, O'Connor, Marie N., Rice, Catherine M., Stemple, Derek, Stephens, Jonathan, Trip, Mieke D., Zwaginga, Jaap-Jan, Samani, Nilesh J., Watkins, Nicholas A., Maguire, Patricia B., Ouwehand, Willem H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996120/
https://ncbi.nlm.nih.gov/pubmed/20833976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-280925
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