Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

In this study, we demonstrate the suitability of the vertebrate Danio rerio (zebrafish) for functional screening of novel platelet genes in vivo by reverse genetics. Comparative transcript analysis of platelets and their precursor cell, the megakaryocyte, together with nucleated blood cell elements,...

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Autori principali: O'Connor, Marie N., Salles, Isabelle I., Cvejic, Ana, Watkins, Nicholas A., Walker, Adam, Garner, Stephen F., Jones, Chris I., Macaulay, Iain C., Steward, Michael, Zwaginga, Jaap-Jan, Bray, Sarah L., Dudbridge, Frank, de Bono, Bernard, Goodall, Alison H., Deckmyn, Hans, Stemple, Derek L., Ouwehand, Willem H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680375/
https://ncbi.nlm.nih.gov/pubmed/19109564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-162693
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