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Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish
The NFE2 transcription factor is expressed in multiple hematopoietic lineages with a well-defined role in regulating megakaryocyte biogenesis and platelet production in mammals. Mice deficient in NFE2 develop severe thrombocytopenia with lethality resulting from neonatal hemorrhage. Recent data in m...
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| Publicado no: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6290098/ https://ncbi.nlm.nih.gov/pubmed/30504234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018021865 |
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