Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish

The NFE2 transcription factor is expressed in multiple hematopoietic lineages with a well-defined role in regulating megakaryocyte biogenesis and platelet production in mammals. Mice deficient in NFE2 develop severe thrombocytopenia with lethality resulting from neonatal hemorrhage. Recent data in m...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Blood Adv
Autores principales: Rost, Megan S., Shestopalov, Ilya, Liu, Yang, Vo, Andy H., Richter, Catherine E., Emly, Sylvia M., Barrett, Francesca G., Stachura, David L., Holinstat, Michael, Zon, Leonard I., Shavit, Jordan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2018
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290098/
https://ncbi.nlm.nih.gov/pubmed/30504234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018021865
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares