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Influence of protein flexibility and peptide conformation on reactivity of monoclonal anti-peptide antibodies with a protein alpha-helix.

Monoclonal antibodies against an alpha-helical region of the iron-containing, oxygen-binding protein myohemerythrin were isolated following immunization of mice with either the whole protein or a peptide homolog of the helix. Three distinct epitopes within the myohemerythrin helix were identified. T...

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Hlavní autoři: Fieser, T M, Tainer, J A, Geysen, H M, Houghten, R A, Lerner, R A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1987
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC299586/
https://ncbi.nlm.nih.gov/pubmed/2446325
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