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Sec53, a protein required for an early step in secretory protein processing and transport in yeast, interacts with the cytoplasmic surface of the endoplasmic reticulum.

The sec53 mutant is a conditional lethal yeast secretory mutant. At 37 degrees C, precursors to exported proteins become firmly attached to the endoplasmic reticulum membrane and are not released into the lumen in a soluble form. The accumulated precursors are insoluble in the detergent Triton X-100...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Ruohola, H, Ferro-Novick, S
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1987
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299565/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3317409/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8468
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