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Folding of Active β-Lactamase in the Yeast Cytoplasm before Translocation into the Endoplasmic Reticulum

Polypeptides targeted to the yeast endoplasmic reticulum (ER) posttranslationally are thought to be kept in the cytoplasm in an unfolded state by Hsp70 chaperones before translocation. We show here that Escherichia coli β-lactamase associated with Hsp70, but adopted a native-like conformation before...

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Detalhes bibliográficos
Main Authors: Paunola, Eija, Suntio, Taina, Jämsä, Eija, Makarow, Marja
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25309/
https://ncbi.nlm.nih.gov/pubmed/9529380
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