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The Cytoplasmic Chaperone Hsp104 Is Required for Conformational Repair of Heat-denatured Proteins in the Yeast Endoplasmic Reticulum

Severe heat stress causes protein denaturation in various cellular compartments. If Saccharomyces cerevisiae cells grown at 24°C are preconditioned at 37°C, proteins denatured by subsequent exposure to 48–50°C can be renatured when the cells are allowed to recover at 24°C. Conformational repair of v...

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Detalhes bibliográficos
Main Authors: Hänninen, Anna-Liisa, Simola, Mari, Saris, Nina, Makarow, Marja
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25649/
https://ncbi.nlm.nih.gov/pubmed/10564260
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