Dynamic chromosomal rearrangements in Hodgkin’s lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles

BACKGROUND: Hodgkin’s lymphoma is characterized by the presence of mono-nucleated Hodgkin cells and bi- to multi-nucleated Reed-Sternberg cells. We have recently shown telomere dysfunction and aberrant synchronous/asynchronous cell divisions during the transition of Hodgkin cells to Reed-Sternberg c...

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Main Authors: Guffei, Amanda, Sarkar, Rahul, Klewes, Ludger, Righolt, Christiaan, Knecht, Hans, Mai, Sabine
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ferrata Storti Foundation 2010
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995561/
https://ncbi.nlm.nih.gov/pubmed/20823137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.030171
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