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Acetylated microtubules are required for fusion of autophagosomes with lysosomes

BACKGROUND: Autophagy is a dynamic process during which isolation membranes package substrates to form autophagosomes that are fused with lysosomes to form autolysosomes for degradation. Although it is agreed that the LC3II-associated mature autophagosomes move along microtubular tracks, it is still...

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Autors principals: Xie, Rui, Nguyen, Susan, McKeehan, Wallace L, Liu, Leyuan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995476/
https://ncbi.nlm.nih.gov/pubmed/21092184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-89
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