Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma

The bone marrow (BM) microenvironment consists of extracellular-matrix and the cellular compartment including immune cells. Multiple myeloma (MM) cell and BM accessory cell interaction promotes MM survival via both cell-cell contact and cytokines. Immunomodulatory agents (IMiDs) target not only MM c...

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Autori principali: Görgün, Güllü, Calabrese, Elisabetta, Soydan, Ender, Hideshima, Teru, Perrone, Giulia, Bandi, Madhavi, Cirstea, Diana, Santo, Loredana, Hu, Yiguo, Tai, Yu-Tzu, Nahar, Sabikun, Mimura, Naoya, Fabre, Claire, Raje, Noopur, Munshi, Nikhil, Richardson, Paul, Anderson, Kenneth C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995353/
https://ncbi.nlm.nih.gov/pubmed/20651070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-279893
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