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ITAM signaling in dendritic cells controls T helper cell priming by regulating MHC class II recycling

Immature dendritic cells (DCs) specialize in antigen capture and maintain a highly dynamic pool of intracellular major histocompatibility complex class II (MHCII) that continuously recycles from peptide loading compartments to the plasma membrane and back again. This process facilitates sampling of...

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Bibliografiske detaljer
Main Authors: Graham, Daniel B., Akilesh, Holly M., Gmyrek, Grzegorz B., Piccio, Laura, Gilfillan, Susan, Sim, Julia, Belizaire, Roger, Carrero, Javier A., Wang, Yinan, Blaufuss, Gregory S., Sandoval, Gabriel, Fujikawa, Keiko, Cross, Anne H., Russell, John H., Cella, Marina, Swat, Wojciech
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995352/
https://ncbi.nlm.nih.gov/pubmed/20634378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-250415
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