ITAM signaling in dendritic cells controls T helper cell priming by regulating MHC class II recycling

Immature dendritic cells (DCs) specialize in antigen capture and maintain a highly dynamic pool of intracellular major histocompatibility complex class II (MHCII) that continuously recycles from peptide loading compartments to the plasma membrane and back again. This process facilitates sampling of...

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Autors principals: Graham, Daniel B., Akilesh, Holly M., Gmyrek, Grzegorz B., Piccio, Laura, Gilfillan, Susan, Sim, Julia, Belizaire, Roger, Carrero, Javier A., Wang, Yinan, Blaufuss, Gregory S., Sandoval, Gabriel, Fujikawa, Keiko, Cross, Anne H., Russell, John H., Cella, Marina, Swat, Wojciech
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995352/
https://ncbi.nlm.nih.gov/pubmed/20634378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-250415
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