ITAM signaling in dendritic cells controls T helper cell priming by regulating MHC class II recycling

Immature dendritic cells (DCs) specialize in antigen capture and maintain a highly dynamic pool of intracellular major histocompatibility complex class II (MHCII) that continuously recycles from peptide loading compartments to the plasma membrane and back again. This process facilitates sampling of...

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Hlavní autoři: Graham, Daniel B., Akilesh, Holly M., Gmyrek, Grzegorz B., Piccio, Laura, Gilfillan, Susan, Sim, Julia, Belizaire, Roger, Carrero, Javier A., Wang, Yinan, Blaufuss, Gregory S., Sandoval, Gabriel, Fujikawa, Keiko, Cross, Anne H., Russell, John H., Cella, Marina, Swat, Wojciech
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995352/
https://ncbi.nlm.nih.gov/pubmed/20634378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-250415
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