ITAM signaling in dendritic cells controls T helper cell priming by regulating MHC class II recycling

Immature dendritic cells (DCs) specialize in antigen capture and maintain a highly dynamic pool of intracellular major histocompatibility complex class II (MHCII) that continuously recycles from peptide loading compartments to the plasma membrane and back again. This process facilitates sampling of...

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Detalhes bibliográficos
Main Authors: Graham, Daniel B., Akilesh, Holly M., Gmyrek, Grzegorz B., Piccio, Laura, Gilfillan, Susan, Sim, Julia, Belizaire, Roger, Carrero, Javier A., Wang, Yinan, Blaufuss, Gregory S., Sandoval, Gabriel, Fujikawa, Keiko, Cross, Anne H., Russell, John H., Cella, Marina, Swat, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995352/
https://ncbi.nlm.nih.gov/pubmed/20634378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-250415
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