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Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function.
In the presence of cyclic AMP, the catabolite activator protein (CAP) of Escherichia coli binds DNA and stimulates transcription at a number of promoters. We have examined a model of CAP bound at the gal promoter and, using directed mutagenesis, have isolated CAP mutants that are analogous to the la...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1987
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299533/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2825186/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8315 |
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