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Mechanism of Initiation of Repression of In Vitro Transcription of the Lac Operon of Escherichia coli

A cyclic AMP-binding protein (CAP protein), cyclic AMP, and RNA polymerase holoenzyme are shown to initiate lac transcription at the lac promoter. Lac repressor appears to control transcription by preventing RNA polymerase and/or CAP protein from binding to the lac promoter. Results support the idea...

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Detalhes bibliográficos
Main Authors: Eron, Larry, Block, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC389302/
https://ncbi.nlm.nih.gov/pubmed/4331560
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