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Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function.

In the presence of cyclic AMP, the catabolite activator protein (CAP) of Escherichia coli binds DNA and stimulates transcription at a number of promoters. We have examined a model of CAP bound at the gal promoter and, using directed mutagenesis, have isolated CAP mutants that are analogous to the la...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Irwin, N, Ptashne, M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1987
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2825186/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8315
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