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Ex3αERKO Male Infertility Phenotype Recapitulates the αERKO Male Phenotype
Disruption of the Esr1 gene encoding estrogen receptor alpha (ERα) by insertion of a neomycin resistance gene (neo) into exon 2 (αERKO mice) was shown previously to cause infertility in male mice. While full-length ERα protein was not expressed in αERKO mice, alternative splicing resulted in the low...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995255/ https://ncbi.nlm.nih.gov/pubmed/20833731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0290 |
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