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Ex3αERKO Male Infertility Phenotype Recapitulates the αERKO Male Phenotype

Disruption of the Esr1 gene encoding estrogen receptor alpha (ERα) by insertion of a neomycin resistance gene (neo) into exon 2 (αERKO mice) was shown previously to cause infertility in male mice. While full-length ERα protein was not expressed in αERKO mice, alternative splicing resulted in the low...

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Detalhes bibliográficos
Main Authors: Goulding, Eugenia H., Hewitt, Sylvia C., Nakamura, Noriko, Hamilton, Katherine, Korach, Kenneth S., Eddy, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995255/
https://ncbi.nlm.nih.gov/pubmed/20833731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0290
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