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Ex3αERKO Male Infertility Phenotype Recapitulates the αERKO Male Phenotype

Disruption of the Esr1 gene encoding estrogen receptor alpha (ERα) by insertion of a neomycin resistance gene (neo) into exon 2 (αERKO mice) was shown previously to cause infertility in male mice. While full-length ERα protein was not expressed in αERKO mice, alternative splicing resulted in the low...

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Bibliographic Details
Main Authors: Goulding, Eugenia H., Hewitt, Sylvia C., Nakamura, Noriko, Hamilton, Katherine, Korach, Kenneth S., Eddy, Edward M.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995255/
https://ncbi.nlm.nih.gov/pubmed/20833731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0290
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