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Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes
Actin polymerization drives the extension of pseudopods that trap and engulf phagocytic targets. The polymerized actin subsequently dissociates as the phagocytic vacuole seals and detaches from the plasma membrane. We found that phagosomes formed by engagement of integrins that serve as complement r...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995177/ https://ncbi.nlm.nih.gov/pubmed/21115805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004005 |
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