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Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes

Actin polymerization drives the extension of pseudopods that trap and engulf phagocytic targets. The polymerized actin subsequently dissociates as the phagocytic vacuole seals and detaches from the plasma membrane. We found that phagosomes formed by engagement of integrins that serve as complement r...

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Autori principali: Bohdanowicz, Michal, Cosío, Gabriela, Backer, Jonathan M., Grinstein, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995177/
https://ncbi.nlm.nih.gov/pubmed/21115805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004005
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