Drosophila Boi limits Hedgehog levels to suppress follicle stem cell proliferation

Stem cells depend on signals from cells within their microenvironment, or niche, as well as factors secreted by distant cells to regulate their maintenance and function. Here we show that Boi, a Hedgehog (Hh)-binding protein, is a novel suppressor of proliferation of follicle stem cells (FSCs) in th...

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Hlavní autoři: Hartman, Tiffiney R., Zinshteyn, Daniel, Schofield, Heather K., Nicolas, Emmanuelle, Okada, Ami, O'Reilly, Alana M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995164/
https://ncbi.nlm.nih.gov/pubmed/21098113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007142
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