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Opposing action of Hedgehog and Insulin signaling balances proliferation and autophagy to determine Follicle Stem Cell Lifespan
Egg production declines with age in many species, a process linked with stem cell loss. Diet-dependent signaling has emerged as critical for stem cell maintenance during aging. Follicle Stem Cells (FSCs) in the Drosophila ovary are exquisitely responsive to diet-induced signals including Hedgehog (H...
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| Pubblicato in: | Dev Cell |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6159899/ https://ncbi.nlm.nih.gov/pubmed/30197240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.08.008 |
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