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Targeted rapid amplification of cDNA ends (T-RACE)—an improved RACE reaction through degradation of non-target sequences

Amplification of the 5′ ends of cDNA, although simple in theory, can often be difficult to achieve. We describe a novel method for the specific amplification of cDNA ends. An oligo-dT adapter incorporating a dUTP-containing PCR primer primes first-strand cDNA synthesis incorporating dUTP. Using the...

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Detalles Bibliográficos
Autores principales: Bower, Neil I., Johnston, Ian A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995088/
https://ncbi.nlm.nih.gov/pubmed/20846956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq816
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