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Screening Target Specificity of siRNAs by Rapid Amplification of cDNA Ends (RACE) for Non-Sequenced Species

RNA interference (RNAi) is the process of sequence-specific posttranslational gene silencing triggered by double-stranded RNAs (dsRNAs). RNAi is a widely used approach for studying gene function. However, studies have shown that using siRNA can lead to off-target effects when the siRNA contains suff...

詳細記述

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書誌詳細
主要な著者: Sabirzhanov, Boris, Sabirzhanova, Inna B., Keifer, Joyce
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992891/
https://ncbi.nlm.nih.gov/pubmed/21437668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-011-9514-6
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