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A model in vitro system for co-transcriptional splicing

A hallmark of metazoan RNA polymerase II transcripts is the presence of numerous small exons surrounded by large introns. Abundant evidence indicates that splicing to excise introns occurs co-transcriptionally, prior to release of the nascent transcript from RNAP II. Here, we established an efficien...

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Hlavní autoři: Yu, Yong, Das, Rita, Folco, Eric G., Reed, Robin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995048/
https://ncbi.nlm.nih.gov/pubmed/20631007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq620
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