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A model in vitro system for co-transcriptional splicing

A hallmark of metazoan RNA polymerase II transcripts is the presence of numerous small exons surrounded by large introns. Abundant evidence indicates that splicing to excise introns occurs co-transcriptionally, prior to release of the nascent transcript from RNAP II. Here, we established an efficien...

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Detalhes bibliográficos
Main Authors: Yu, Yong, Das, Rita, Folco, Eric G., Reed, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995048/
https://ncbi.nlm.nih.gov/pubmed/20631007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq620
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