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The Future of Toxicity Testing: A Focus on In Vitro Methods Using a Quantitative High Throughput Screening Platform

The U.S. Tox21 collaborative program represents a paradigm shift in toxicity testing of chemical compounds from traditional in vivo tests to less expensive and higher throughput in vitro methods to prioritize compounds for further study, identify mechanisms of action, and ultimately develop predicti...

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Bibliographic Details
Main Authors: Shukla, Sunita J., Huang, Ruili, Austin, Christopher P., Xia, Menghang
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994991/
https://ncbi.nlm.nih.gov/pubmed/20708096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2010.07.007
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