Transient development of ovotestes in XX Sox9 transgenic mice

The sex of an individual results from the paternal transmission of the SRY gene located on the Y chromosome. In turn, SRY initiates Sox9 expression, a transcription factor required for testicular differentiation. Ectopic activation of SOX9 in XX Wt1:Sox9 transgenic mice, induces female-to-male sex r...

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Main Authors: Gregoire, Elodie P., Lavery, Rowena, Chassot, Anne-Amandine, Akiyama, Haruhiko, Treier, Mathias, Behringer, Richard R., Chaboissier, Marie-Christine
格式: Artigo
語言:Inglês
出版: 2010
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993827/
https://ncbi.nlm.nih.gov/pubmed/20965161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.10.006
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