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The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

To examine whether the transcription factor Sox9 has an essential role during the sequential steps of chondrocyte differentiation, we have used the Cre/loxP recombination system to generate mouse embryos in which either Sox9 is missing from undifferentiated mesenchymal cells of limb buds or the Sox9...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Akiyama, Haruhiko, Chaboissier, Marie-Christine, Martin, James F., Schedl, Andreas, de Crombrugghe, Benoit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC187468/
https://ncbi.nlm.nih.gov/pubmed/12414734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1017802
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